Brian Michael Bendis’ comic Powers is about police in a city with superheroes but it’s a bit cartoonier and with more of a wink/nudge to the genre than Gotham Central. I’ve read some of the series in the dark mists of time, so I’m not very steeped in the metaplot, but in Psychotic there’s a serial killer after Powers.
It’s interesting because superpowers have been outlawed at this point, but some vigilantes are coming back with them, making a stand. Detective Christian Walker used to be a Power, and now he’s coaching the new Retro Girl. There’s a great TV interview sequence where the constitutionality of a law against a certain kind of people is brought up, specifically compared to a law against being Latino, which is interesting. Detective Deena Pilgrim is being harassed by an ex-boyfriend, and neighbourhood favourite Power the Blackguard has been killed.
It’s a good twisty little investigation and stuff is set up for future volumes. If the Vancouver Public Library hadn’t cut off my ability to place hold on items for free, I would be seeking the rest of the books out right now.